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IL6 — TCF15

Text-mined interactions from Literome

Carlquist et al., J Infect Dis 1999 : Cytomegalovirus induction of interleukin-6 in lung fibroblasts occurs independently of active infection and involves a G protein and the transcription factor , NF-kappaB
Solís-Herruzo et al., J Biol Chem 1999 : Interleukin-6 increases rat metalloproteinase-13 gene expression through stimulation of activator protein 1 transcription factor in cultured fibroblasts
Debonera et al., J Surg Res 2001 : Activation of the latent transcription factor , STAT3, is dependent on IL-6 release
Jeong et al., Cytokine 2002 : Expression of TNF-alpha and IL-6 was regulated by a transcription factor , nuclear factor (NF)-kappaB
McDermott et al., Trends Mol Med 2002 (Familial Mediterranean Fever...) : Disorders of interleukin-1 processing and of regulation of nuclear factor kappaB transcription factor , and possibly defective apoptosis, might be involved in the pathogenesis of all but one of these disorders
Tamaoki et al., Am J Med 2004 (Chronic Disease...) : Macrolides inhibit the production of many proinflammatory cytokines, such as interleukin (IL)-1, IL-6 , IL-8, and tumor necrosis factor-alpha, perhaps by suppressing the transcription factor nuclear factor-kappaB or activator protein-1
Siore et al., Am J Physiol Lung Cell Mol Physiol 2005 (Disease Models, Animal...) : We monitored pulmonary vascular resistance, oxygenation, neutrophil count, lung edema as reflected by wet-dry weights of lung tissue, perfusate concentrations of TNF-alpha, IL-6 , and 8-isoprostane ( a marker of oxidative stress ), and activation of the transcription factor ( NF-kappaB ) in lung tissue before and for 2 h after endotoxin
Ajuwon et al., J Nutr 2005 : Palmitate activates the NF-kappaB transcription factor and induces IL-6 and TNFalpha expression in 3T3-L1 adipocytes
Kino et al., Eur J Clin Invest 2007 (Acute-Phase Reaction...) : Overexpression of PPARdelta enhanced the suppressive effect of GW501516 on STAT3 activated transcriptional activity of the alpha1-antichymotrypsin promoter, while GW501516 suppressed interleukin-6 induced binding of this transcription factor to this promoter
Chen et al., Immunol Res 2008 (Bacterial Infections) : In the mouse, the differentiation of this new lineage is initiated by TGFbeta-1 and IL-6 and IL-21, which activate Stat3 and induce the expression of the transcription factor retinoic acid related orphan receptor ( RORgammat )
Sheikh et al., Hepatology 2008 (Hepatitis C...) : This transcription factor plays a key role in the expression of cytokines, tumor necrosis factor alpha (TNF-alpha), interleukin 6, interleukin 8, tumor growth factor beta, and Fas ligand ... This transcription factor plays a key role in the expression of cytokines, tumor necrosis factor alpha (TNF-alpha), interleukin 6 , interleukin 8, tumor growth factor beta, and Fas ligand
Chen et al., Immunity 2008 (Arthritis, Rheumatoid...) : IRF-4 binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor
Maeda et al., Blood 2009 (Disease Models, Animal...) : IL-6 stimulation caused uncommitted progenitors to express the Id1 transcription factor , which is known to inhibit lymphopoiesis and elevate myelopoiesis, and its expression was MAPK dependent
Saraiva et al., Immunity 2009 : Interleukin-10 production by Th1 cells requires interleukin-12 induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose
Iliopoulos et al., Cell 2009 (Inflammation) : IL6 mediated activation of the STAT3 transcription factor is necessary for transformation, and IL6 activates NF-kappaB, thereby completing a positive feedback loop
Park et al., PloS one 2012 : The present study investigates the involvement of the IL-6 family of cytokines, activation of the transcription factor Signal Transducer and Activator of Transcription-3 ( STAT3 ), and the role of Suppressor Of Cytokine Signaling-3 ( SOCS3 ) in regulating excitotoxic neuronal death in vitro
Shimizu et al., Mol Cell Biol 1990 (Chromosome Deletion...) : Involvement of a NF-kappa B-like transcription factor in the activation of the interleukin-6 gene by inflammatory lymphokines
Lütticken et al., FEBS Lett 1995 : The cytokine interleukin-6 (IL-6) rapidly activates a latent cytoplasmic transcription factor , acute-phase response factor ( APRF ), by tyrosine phosphorylation
Begley et al., Stem Cells 1994 (Leukemia-Lymphoma, Adult T-Cell) : The SCL transcription factor and differential regulation of macrophage differentiation by LIF, OSM and IL-6
Wegenka et al., Mol Cell Biol 1994 (Carcinoma, Hepatocellular...) : We have shown recently that IL-6 and leukemia inhibitory factor rapidly activate a latent cytoplasmic transcription factor , acute-phase response factor ( APRF ), by tyrosine phosphorylation, which then binds to IL-6 response elements of various IL-6 target genes
Sung et al., J Biol Chem 1993 : Stimulation of interleukin-1 gene transcription may be caused by the stimulation of transcription factor activities, including those of AP-1, by these protein phosphatase inhibitors
Faggioli et al., Biochem Biophys Res Commun 1997 : Protein synthesis inhibitors cycloheximide and anisomycin induce interleukin-6 gene expression and activate transcription factor NF-kappaB