Gene interactions and pathways from curated databases and text-mining

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PTBP1 — XRN1

Text-mined interactions from Literome

Woo et al., Nucleic Acids Res 2009 : This report on the regulation of mper2 proposes that post-transcriptional mRNA decay mediated by PTB is a fine tuned regulatory mechanism that includes dampening-down effects during circadian mRNA oscillations
Lin et al., J Cell Biol 2011 : Here we show that down-regulation of PTB and its neuronal analogue nPTB during muscle cell differentiation may involve alternative splicing coupled nonsense mediated mRNA decay
Sinturel et al., Proc Natl Acad Sci U S A 2012 : Activation of 5'-3 ' exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast ... A cytoplasmic 5'-3 ' exoribonuclease activity is therefore essential for yeast growth on glycerol, suggesting that Xrn1 activation by Dcs1 is physiologically important ... Therefore, we propose that the activation of Xrn1 by Dcs1 is important for respiration