Gene interactions and pathways from curated databases and text-mining

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DEFB4B — TLR2

Text-mined interactions from Literome

Birchler et al., Eur J Immunol 2001 : Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein
Hertz et al., J Immunol 2003 : Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2
Vora et al., J Immunol 2004 : Beta-defensin-2 expression is regulated by TLR signaling in intestinal epithelial cells ... LPS and peptidoglycan stimulated beta-defensin-2 promoter activation in a TLR4- and TLR2 dependent manner, respectively
Büchau et al., J Invest Dermatol 2008 : We observed that pimecrolimus enhances distinct expression of cathelicidin, CD14, and human beta-defensin-2 and beta-defensin-3 in response to TLR2/6 ligands
Hussain et al., Am J Physiol Lung Cell Mol Physiol 2008 : Innate immune responses in murine pleural mesothelial cells : Toll-like receptor-2 dependent induction of beta-defensin-2 by staphylococcal peptidoglycan
Mahanonda et al., J Periodontal Res 2009 : Stimulation of HGECs with highly purified TLR2 , 3 or 5 ligands led to expression of hBD-2 and of IL-8
Frei et al., PloS one 2010 : We found that co-expression of MHC class II molecules and TLR2 or TLR4 in human embryonic kidney (HEK) cells 293 leads to enhanced production of the anti-microbial peptide human-beta-defensin (hBD) 2 after treatment with TLR2 stimulus bacterial lipoprotein (BLP) or TLR4 ligand lipopolysaccharide (LPS), respectively