◀ Back to FGF2
FGF2 — TWIST1
Text-mined interactions from Literome
O'Rourke et al., Dev Biol 2002
(Polydactyly) :
Twist plays an essential role in
FGF and SHH signal transduction during mouse limb development
Zuniga et al., Mech Dev 2002
:
Mouse
Twist is
required for
fibroblast growth factor mediated epithelial-mesenchymal signalling and cell survival during limb morphogenesis
Connerney et al., Dev Biol 2008
(Craniosynostoses) :
Twist1 homodimers
enhance FGF responsiveness of the cranial sutures and promote suture closure
Bridges et al., Am J Pathol 2009
(Pulmonary Fibrosis) :
Twist1 was
induced by the profibrotic growth factors ( GFs ) basic
fibroblast growth factor , platelet derived growth factor, and epidermal growth factor in primary rat lung fibroblasts ( RLFs )
Rice et al., Hum Mol Genet 2010
(Craniosynostoses...) :
We show that
FGF2 will
induce Twist1 , normalize osteoprogenitor proliferation and differentiation and rescue the lambdoid suture synostosis in Gli3Xt-J/Xt-J mice
Katoh et al., Curr Pharm Biotechnol 2011
:
Because
FGF , Hedgehog, TGFß, and non-canonical WNT signals synergistically
induce EMT regulators, such as Snail ( SNAI1 ), Slug ( SNAI2 ),
TWIST , and ZEB2 ( SIP1 ), tumor-stromal interaction at the invasion front aids cancer stem cells to acquire more malignant phenotype
Serrano et al., Arch Oral Biol 2011
:
Exogenous
FGF-2 up-regulated Notch 1,
Twist 1 and Twist 2 gene expression in MCC explants from E17 mice, whilst TGF-ß2 had the opposite effect
Lu et al., Dev Dyn 2012
:
Molecular studies on the
roles of Runx2 and
Twist1 in regulating
FGF signaling ... In this study, we assessed the
roles of Runx2 and its functional antagonist
Twist1 in regulating
fibroblast growth factor ( FGF ) signaling using in vitro biochemical approaches