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ANPEP — IL6

Text-mined interactions from Literome

Kido et al., Clin Exp Metastasis 1999 (Bone Neoplasms...) : Competitive RT-PCR and Ala-pNA activity assays revealed that IL-6 and sIL-6R significantly increased the mRNA expression and activity of APN in both osteosarcoma cell lines
Kehlen et al., Cancer Res 2003 (Carcinoma...) : In the undifferentiated thyroid carcinoma cell line 1736, APN/CD13 mRNA expression could be increased by epidermal growth factor, basic fibroblast growth factor, interleukin-6 , and tumor necrosis factor alpha
Neumeier et al., J Leukoc Biol 2006 : However, HMW-APM induces the secretion of interleukin (IL)-6 in human monocytes and THP-1 cells but does not suppress lipopolysaccharide (LPS) induced IL-6 secretion ... In contrast, LMW-APM reduces LPS mediated IL-6 release and furthermore, stimulates IL-10 secretion, most likely by reducing the abundance of inhibitor of nuclear factor (NF)-kappaB kinase beta, leading to a diminished nuclear translocation of NF-kappaB p65
Uji et al., J Surg Res 2010 (Disease Models, Animal...) : APN deficiency resulted in significant increases in the plasma levels of TNF-alpha, IL-6 , and MCP-1 at 24 h after CLP
Alleva et al., Toxicol In Vitro 2011 (MAP Kinase Signaling System) : APM increases the levels of inflammatory mediator IL-6 , VEGF and their soluble receptors released from endothelial cells into the medium
Ponemone et al., Clinical and translational gastroenterology 2010 : APN , but not leptin, increased anti-CD3 induced IL-6 levels in LPL-T only in IBD patients