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IL12B — LANCL1

Text-mined interactions from Literome

Walter et al., J Exp Med 2001 (Asthma...) : Epithelial IL-12 was also inducible during paramyxoviral bronchitis, but in this case, initial IL-12 p70 expression was followed by 75-fold greater expression of IL-12 p40 ( as monomer and homodimer )
Padigel et al., J Immunol 2001 (Leishmaniasis, Cutaneous) : At wk 9 of infection, we detected similar levels of IL-4, IFN-gamma, IL-12p40 , and IL-12Rbeta2 mRNA in draining lymph nodes of healing C57BL/6, CD28 ( -/- ), and CD40L ( -/- ) CD28 ( -/- ) mice, whereas CD40L ( -/- ) mice had increased mRNA levels for IL-4 but reduced levels for IFN-gamma, IL-12p40 , and IL-12Rbeta2
Pascual et al., Infect Immun 2002 : The absence of IL-12 was not due to overt increases in production of either IL-12 p40 or IL-10
Masumi et al., FEBS Lett 2002 : We have previously shown that IL-12p40 expression is impaired in ICSBP-deficient mice and that transfection of ICSBP together with IRF-1 can activate IL-12p40 expression in mouse macrophage cells
Maruyama et al., J Immunol 2003 : While IFN-gamma must be present for IL-12 p40 gene induction , the p35 gene is strongly induced by LPS, even in the absence of IFN-gamma, and therefore the induction of the p35 gene is IRF-1 independent
Boddupalli et al., Free Radic Biol Med 2007 : In activated macrophages, the rel/NF-kappaB transcription factors are known to play important roles in interleukin-12 (IL-12) p40 regulation by nitric oxide ( NO ) ... Here, we describe a dominant role for c-rel involving p38 mitogen activated protein kinase ( p38 MAPK ) and calmodulin (CaM) protein in NO-mediated IL-12 p40 inhibition in activated macrophages
Charmoy et al., J Leukoc Biol 2007 (Disease Susceptibility) : Thus, following infection with L. major, in C57BL/6 mice, PMN could constitute one of the earliest sources of IL-12, and in BALB/c mice, secretion of IL-12p40 could contribute to impaired, early IL-12 signaling
Ryan et al., Vet Immunol Immunopathol 2010 (Actinomycetales Infections...) : On day 12, TNF-a induction in monocyte derived macrophages and IL-12 p40 induction in BAL macrophages infected with R. equi was significantly higher in foals treated with PPVO than in controls
McBerry et al., J Immunol 2012 (Disease Models, Animal...) : p38 MAPK activation and IL-12p70 production was more robust from TFF2 ( -/- ) CD8+ DC compared with WT CD8+ DC and treatment of WT DC with rTFF2 suppressed TLR induced IL-12/23p40 production
Hino et al., Eur J Immunol 1996 : In our experiments, p40 mRNA accumulation was shown to be affected by IL-10 more severely than the accumulation of p35 mRNA, indicating that IL-10 regulates IL-12 production by APC mainly by affecting p40 mRNA accumulation