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IFNG — NOD1
Text-mined interactions from Literome
Hisamatsu et al., J Biol Chem 2003
(Inflammation) :
Interferon-gamma (IFN gamma) , which is a potent pro-inflammatory cytokine in intestinal mucosal inflammation,
activates CARD4/NOD1 mRNA transcription in a time- and dose dependent manner and results in augmentation of CARD4/NOD1 protein in SW480 cells
Tada et al., Infect Immun 2005
:
These findings suggest that
Nod1 and Nod2 agonists in combination with TLR3, TLR4, and TLR9 agonists synergistically
induce IL-12 and
IFN-gamma production in DCs to induce Th1-lineage immune responses
Masumoto et al., J Exp Med 2006
:
Nod1 stimulation did not
induce TNFalpha, interleukin 12, and
interferon gamma , suggesting that the primary role of Nod1 is to induce the recruitment of immune cells
de Jong et al., PLoS Pathog 2012
(Salmonella Infections...) :
The interaction of Salmonella pathogen associated molecular patterns ( PAMPs ) with Toll-like receptors ( TLRs ) and
NOD-like receptors ( NLRs ) leads to inflammasome formation, activation, and recruitment of neutrophils and macrophages and the production of pro-inflammatory cytokines, most notably interleukin (IL)-6, IL-1ß, tumor necrosis factor (TNF)-a, and
interferon-gamma (IFN)-?
Swain et al., J Biosci 2013
(Bacterial Infections) :
In response to both Gram positive and Gram negative bacterial infections,
NOD1 and NOD2 receptors signalling were activated and IL-1 beta, IL-8 and
IFN- gamma were
induced