Gene interactions and pathways from curated databases and text-mining

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IGF2 — NOS1

Text-mined interactions from Literome

Kaliman et al., J Biol Chem 1999 : Here we show that IGF-II induces nuclear factor-kappaB (NF-kappaB) and nitric-oxide synthase (NOS) activities downstream from PI 3-kinase and that these events are critical for myogenesis
Sun et al., Zhonghua Kou Qiang Yi Xue Za Zhi 2004 : [ Effects of insulin-like growth factor II on regulating nitric oxide synthase gene expression in mouse osteoblast-like MC3T3-E1 cells ]
Sun et al., J Zhejiang Univ Sci B 2005 : Effects of IGF-II on promoting proliferation and regulating nitric oxide synthase gene expression in mouse osteoblast-like cell
Ma et al., Biochem Biophys Res Commun 2009 : However, IGF-1 enhanced NOS activity, NO content, and the expression level of cyclin E protein, and reduced the expression level of AT(1) mRNA
Stone et al., J Gerontol A Biol Sci Med Sci 2012 : Moreover, IGF-1 also activated endothelial nitric oxide synthase in human umbilical vein endothelial cells