Gene interactions and pathways from curated databases and text-mining

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ANXA1 — IL10

Text-mined interactions from Literome

Ferlazzo et al., Int Immunopharmacol 2003 : In macrophage ( J774 ) cell line cultures primed with lipolysaccharide (LPS), recombinant ANX-1 stimulated IL-10 release in a dose- and time dependent manner ... In addition, ANX-1 stimulated IL-10 release may also be responsible for the inhibition of IL-12 mRNA expression and, consequently, IL-12 synthesis
Parente et al., Inflamm Res 2004 : The inhibition of iNOS expression may be caused by the stimulation of IL-10 release induced by ANXA1 in macrophages
Schuetze et al., Int Immunol 2005 : Whereas p19 was induced early and transiently, p40 and p35 were up-regulated later and then continuously, but the secretion of IL-23 and IL-12p70 was significantly reduced by IL-10
Souza et al., J Immunol 2007 (Inflammation...) : The required role of endogenously produced lipoxin A4 and annexin-1 for the production of IL-10 and inflammatory hyporesponsiveness in mice