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MYL6 — PXN
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
MYL6
→
PXN
(reaction)
Kumar et al., Biochemistry 1989, Cavaillé et al., Eur J Biochem 1986
-
Reactome Reaction:
MYL6
→
PXN
(indirect_complex)
Morgan et al., J Appl Physiol 2001, Marston et al., Biochem J 1991, Kumar et al., Biochemistry 1989, Mohammad et al., Biochem J 1989, Cavaillé et al., Eur J Biochem 1986
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Tang et al., J Physiol 2002
:
Paxillin antisense selectively depressed paxillin expression, but it did not
affect the expression of vinculin, focal adhesion kinase, myosin light chain kinase, myosin heavy chain or
myosin light chain ... The depletion of
paxillin did not
inhibit the increase in intracellular free Ca2+,
myosin light chain phosphorylation or myosin ATPase activity in response to contractile stimulation
Tang et al., J Physiol 2003
:
Expression of the
paxillin mutants F31, F118 or F31/118 inhibited the contractile response to ACh stimulation but did not
inhibit the increase in
myosin light chain phosphorylation
Birukova et al., Am J Respir Cell Mol Biol 2009
:
SiRNA based
paxillin knockdown
attenuated VEGF induced EC permeability,
myosin light chain phosphorylation, and stress fiber and paracellular gap formation