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NGF — PTGS2
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Fehrenbacher et al., Pain 2005
:
The basal and TNFalpha induced expression of
COX-2 was not
dependent on the presence of
NGF in the growth media
Jang et al., BJU Int 2006
(Urinary Incontinence) :
To examine the
effects of intravesical
cyclooxygenase-2 (COX-2) inhibitors on the expression of inducible nitric oxide synthase (iNOS) and
nerve growth factor (NGF) in cyclophosphamide ( CYP ) -induced overactive bladder ( OAB )
Alimasi et al., Spine (Phila Pa 1976) 2013
:
Regulation of
nerve growth factor by anti-inflammatory drugs, a steroid, and a selective
cyclooxygenase 2 inhibitor in human intervertebral disc cells stimulated with interleukin-1
Murase et al., J Physiol 2013
(Hyperalgesia) :
COX-2 inhibitors did not
suppress NGF upregulation after LC
Tada et al., J Immunol 1998
:
A type IIA sPLA2 inhibitor, but neither cytosolic PLA2 nor COX inhibitors, reduced, while adding exogenous type IIA sPLA2 augmented,
NGF induced
COX-2 expression and its attendant PGD2 generation, indicating that the sPLA2 mediated increase in delayed PGD2 generation was attributable mainly to enhanced COX-2 expression ... Type IIA sPLA2 and its close relative type V sPLA2 associated with fibroblastic cell surfaces increased
NGF induced
COX-2 expression more efficiently than the soluble enzymes, revealing a particular juxtacrine sPLA2 presentation route