Koyama et al., Anticancer Res 2004
(Bone Neoplasms...) :
Enforced expression of Id3 caused the MG-63 sarcoma cells to be more sensitive to CDDP induced growth inhibition, through generation of ROS and caspase-3 activation
Kee et al., J Immunol 2005
:
We hypothesize that Id3 induces activation of caspase-2 as a consequence of severe or `` catastrophic '' growth arrest