Gene interactions and pathways from curated databases and text-mining

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BCR — PKD3

Text-mined interactions from Literome

Haxhinasto et al., J Immunol 2003 : In this study, we show that genetic or pharmacologic inhibition of BCR mediated PKD activation in B lymphocytes abrogated the synergy between the CD40 and the BCR, as measured by activation of Ig and cytokine secretion
Vigorito et al., Cell Signal 2006 : We found that PKD activation upon BCR engagement or coligation of the BCR with CD19 is entirely dependent on PI3K and PLCgamma but differ in the requirement for Vav proteins
Pracht et al., Cell Signal 2007 : Finally, splenocytes from PKC-delta-deficient mice are found to exert reduced phosphorylation of PKD ( a.k.a. PKC-mu ) in response to BCR engagement, suggesting the early, membrane-proximal activation of an attenuating kinase complex including PKC-delta and PKD