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CD4 — CXCR3

Text-mined interactions from Literome

Mognetti et al., Clin Exp Immunol 2000 (Acquired Immunodeficiency Syndrome) : CD4 expression was detected in five of the 10 placentas, while membrane protein expression of CCR3, CXCR4 and CCR5 was detected in every case, despite quantitative differences among individuals
Rabin et al., J Immunol 2003 (Inflammation) : We next investigated the role of CXCR3 on peripheral effector/memory CD4 ( + ) T cells by comparing its pattern of expression with that of CCR5, another Th1-cell associated chemokine receptor
Mohan et al., Eur J Immunol 2005 (Dermatitis...) : Blocking CXCR3 inhibited recruitment of 60-85 % of unstimulated T cells and up to 90 % of CD8 ( + ) CD45RC ( + ) effector T cells, but caused < 50 % inhibition of CD4 ( + ) and CD8 ( + ) memory ( CD45RC ( - ) ) T cells
Rahangdale et al., J Immunol 2006 : In this study we demonstrate that IL-16/CD4 induced receptor desensitization of CXCR3 on primary human T cells ... IL-16/CD4 stimulation does not result in surface modulation of CXCR3 or changes in CXCL10 binding affinity
Stiles et al., Eur J Immunol 2006 (Acute Disease...) : Differential roles for CXCR3 in CD4+ and CD8+ T cell trafficking following viral infection of the CNS
Garcia et al., Allergy 2007 (Aspergillosis, Allergic Bronchopulmonary...) : Upon Asp f exposure, proliferating CD4 ( + ) T cells from ABPA patients down-regulated the expression of CCR4 and CXCR3 while CCR4 and CXCR3 were up-regulated in allergen-specific T cells from non-ABPA allergic asthmatics
Campanella et al., J Immunol Methods 2008 (Inflammation) : We describe here the development of a robust in vivo recruitment assay for CD8 ( + ) and CD4 ( + ) T lymphocytes induced by the CXCR3 ligands IP-10 (CXCL10) and I-TAC ( CXCL11 )
Elyaman et al., Am J Pathol 2008 (Encephalomyelitis, Autoimmune, Experimental) : We found that memory CD4 ( + ) T cells up-regulated the activation marker CD44 as well as CXCR3 and ICOS, proliferated more and produced more interferon-gamma and less interleukin-17 compared to effector T cells