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RAC2 — SLC2A4RG

Text-mined interactions from Literome

Takuwa et al., Biochim Biophys Acta 2002 : Edg5 mediated Rac inhibition involves stimulation of Rac-GTPase activating protein (GAP) activity, rather than inhibition of Rac-guanine nucleotide exchange factor (GEF) activity
Buchsbaum et al., J Biol Chem 2003 : Tiam1 is a ubiquitous guanine nucleotide exchange factor (GEF) that activates the Rac GTPase
Lu et al., Nature structural & molecular biology 2004 : These data reveal a new mode of action of PH domains and a novel, evolutionarily conserved mechanism by which a bipartite GEF can activate Rac
Sato et al., Cancer Sci 2005 : The activation of Cdc42 and Rac by the trans-interaction of nectin and nectin is mediated by c-Src, another small G protein, Rap1, a Cdc42-GEF , FRG, and a Rac-GEF, Vav2
Santy et al., Curr Biol 2005 : We report here that ARNO dependent activation of Rac is mediated by a bipartite Rac GEF , the Dock180/Elmo complex
Strumane et al., Methods Enzymol 2006 (Skin Neoplasms) : The Tiam1 gene encodes a guanine nucleotide exchange factor (GEF) that specifically activates the Rho-like GTPase Rac
Chen et al., Proc Natl Acad Sci U S A 2011 : In cultured mammalian cells, RAC1 is activated by increased TRIO 's GEF activity when DISC1 is present