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EPHB2 — SMCP

Text-mined interactions from Literome

Yang et al., J Cell Biol 2004 (Melanoma) : Expression of MCSP enhances integrin mediated cell spreading, FAK phosphorylation, and activation of ERK1/2 ... Enhanced activation of FAK and ERK1/2 by MCSP appears to involve independent mechanisms because inhibition of FAK activation had no effect on ERK1/2 phosphorylation
Yang et al., Cancer Res 2009 (MAP Kinase Signaling System...) : MCSP expression in melanoma cells enhances integrin function and constitutive activation of Erk1,2 ... The results show that MCSP expression in radial growth phase, vertical growth phase, or metastatic cell lines causes sustained activation of Erk1,2 , enhanced growth, and motility which all require the cytoplasmic domain of the MCSP core protein