Gene interactions and pathways from curated databases and text-mining

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LGALS3 — PIK3R1

Text-mined interactions from Literome

MacKinnon et al., J Immunol 2008 : Galectin-3 binds to CD98, and exogenous galectin-3 or cross linking CD98 with the mAb 4F2 stimulates PI3K activation and alternative activation
Rotshenker et al., Glia 2008 (Demyelinating Diseases...) : S-trans, trans-farnesylthiosalicylic (FTS), which inhibits Galectin-3/MAC-2 dependent activation of PI3K through Ras, inhibited phagocytosis ... A role for Galectin-3/MAC-2 dependent activation of PI3K through Ras, mostly K-Ras, is thus suggested
Baatar et al., Brain Behav Immun 2009 : Tregs utilize beta-galactoside binding protein to transiently inhibit PI3K/p21ras activity of human CD8+ T cells to block their TCR mediated ERK activity and proliferation