Gene interactions and pathways from curated databases and text-mining

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CYR61 — TNF

Text-mined interactions from Literome

Gashaw et al., Endocrinology 2008 : CYR61 mRNA expression was further regulated by IL-1, TNFalpha , PGE2, and PGF2alpha ... The opposite effect of TNFalpha combined with hypoxia on CYR61 up-regulation could contribute to a balanced expression level of this angiogenic factor in the endometrium
Lin et al., J Endod 2009 (Alveolar Bone Loss...) : The study assessed the effect of simvastatin on tumor necrosis factor alpha (TNF- alpha) induced synthesis of Cyr61 and CCL2 in MG-63 human osteoblastic cells ... Western blot showed that TNF-alpha stimulated Cyr61 synthesis in MG-63, whereas simvastatin attenuated this effect in a dose dependent manner
Lee et al., J Endod 2010 (Alveolar Bone Loss...) : In the study we examined the effect of major histocompatibility complex class II transactivator (CIITA) on tumor necrosis factor (TNF)-alpha induced Cyr61 synthesis in U2OS human osteoblastic cells by Western blot analysis
Kok et al., Arthritis Rheum 2013 (Arthritis, Experimental...) : In RASFs, simvastatin suppressed the tumor necrosis factor a (TNFa) induced production of CYR-61 and CCL20
Lin et al., J Endod 2013 : We assessed tumor necrosis factor (TNF)-a stimulated expression of Cyr61 and phosphorylated inactive FoxO3a ( p-FoxO3a ) in MC3T3-E1 murine osteoblasts by Western analysis ... Forced expression of FoxO3a reduced TNF-a stimulated Cyr61 synthesis