Morand et al., Mediators Inflamm 2006
(Arthritis, Rheumatoid) :
Interleukin (IL)-1beta also induced annexin I translocation and mRNA but also increased intracellular protein
Tang et al., PloS one 2011
:
The results show that Annexin A1 can negatively regulate phosphorylation of p38 and release of IL-1ß , IL-6 and TNF-a in THP-1 cells following propofol intervention and lipopolysaccharide (LPS) stimulation ... Our results clearly indicate that propofol can up-regulate Annexin A1 to inhibit the phosphorylation level of p38 and release of IL-1ß , IL-6 and TNF-a, so as to inhibit inflammatory response