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Aziziyeh et al., Cell Signal 2009
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We show that the small GTPase RalA associates with both LPA ( 1 ) and LPA ( 2 ) in human embryonic kidney ( HEK 293 ) cells and that stimulation of LPA ( 1 ) receptors with LPA triggers the activation of RalA Hofer et al., Curr Biol 1998
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Lysophosphatidic acid (LPA) and epidermal growth factor (EGF), which activate both Ras dependent and Ras independent signaling pathways [ 10,11 ], rapidly activated Ral