Gene interactions and pathways from curated databases and text-mining

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IL1B — IRF1

Text-mined interactions from Literome

Teng et al., Am J Physiol Cell Physiol 2002 : Conversely, IFN-gamma, but not IL-1 beta , induced signal transducer and activator of transcription ( STAT ) 1 and interferon regulatory factor (IRF)-1 binding
Lee et al., Cancer Res 2005 (MAP Kinase Signaling System) : We found that IL-1beta regulated IRF-1 gene expression through stimulation of p38 mitogen activated protein kinase ( MAPK ), which mediated signal transducer and activator of transcription 1 ( Stat1 ) serine phosphorylation and Stat1 nuclear translocation to activate the IRF-1 promoter
Flodström et al., Endocrinology 1997 : IL-1beta alone induced a marginal and transient increase in IRF-1 ... It has been previously reported that nicotinamide prevents IL-1beta induced IRF-1 expression in rat pancreatic islets
Blanch et al., J Immunol 1999 : We now report that levels of IRF-1 and pIgR mRNA are coordinately regulated in HT-29 cells by TNF-alpha, IFN-gamma, and IL-1beta