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AQP3 — INS

Text-mined interactions from Literome

Asai et al., Biol Pharm Bull 2006 : Therefore we first investigated whether insulin regulating the glycolytic pathway took part in glycerol transport through AQP3 in the gastrointestinal tract and found that insulin significantly suppressed mRNA and protein expressions of AQP3 in Caco-2 cells
Higuchi et al., J Cell Biochem 2007 : Transcriptional regulation of aquaporin 3 by insulin ... A mutant reporter plasmid with an altered Foxa2 binding site and siRNA for the Foxa2 sequence counteracted the insulin mediated repression of AQP3 transcription ... These results suggest that Foxa2 is one of the transcriptional regulators for AQP3 gene expression regulated by insulin
Rodríguez et al., J Clin Endocrinol Metab 2011 (Obesity...) : The impact of obesity and obesity associated type 2 diabetes as well as the potential regulatory role of insulin and leptin on aquaglyceroporins (AQP) 3 , 7, and 9 were analyzed ... The translocation of AQP in response to insulin and isoproterenol was analyzed by immunocytochemistry ... Insulin up-regulated all AQP , whereas leptin up-regulated AQP3 and down-regulated AQP7 and AQP9 in adipocytes and hepatocytes ... Our findings show, for the first time, that insulin and leptin regulate the AQP through the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway in human visceral adipocytes and hepatocytes