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DIO2 — INS
Text-mined interactions from Literome
Brabant et al., FASEB J 2005
(Insulin Resistance...) :
In
diet induced obesity ( DIO ) , hepatic
insulin signaling is
impaired but the link between leptin and insulin signaling pathways is only incompletely defined ... The aim of the present study was to evaluate the
effects of
DIO on leptin and
insulin cross signaling in the liver
Levin et al., Am J Physiol Regul Integr Comp Physiol 2005
(Disease Models, Animal...) :
The
DIO phenotype and exaggerated
insulin response to oral glucose in the nonobese, chow fed state persisted in the F6 generation
Ropelle et al., J Physiol 2006
(Insulin Resistance...) :
Diet induced obesity ( DIO ) increased the expression and activity of the protein tyrosine phosphatase 1B (PTP1B) and
attenuated insulin signalling in gastrocnemius muscle of rats, a phenomenon which was reversed by a single session of exercise
Begg et al., Endocrinology 2013
(Anorexia...) :
However, after a peripheral bolus injection of insulin, cerebrospinal fluid
insulin increased in Con and
DIO-rev rats but not in the DIO group