◀ Back to ATM

ATM — E2F1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: E2F1 → ATM (increases, E2F1 Activity)
  Evidence: In response to genotoxic stress (i.e. DNA-damaging agents), the E2F1 protein is stabilized through distinct mechanisms including: (i) direct phosphorylation by ataxia-telangiectasia- mutated (ATM) kinase, ATM- and RAD3-related (ATR) kinase and checkpoint 2 (CHK2) kinase and (ii) acetylation through p300/CREB-binding-proteinassociated factor (P/CAF)
• OpenBEL Selventa BEL large corpus: E2F1 → ATM (directlyIncreases, E2F1 Activity) Lin et al., Genes Dev 2001*
  Evidence: PhosphoElm data from PMID 15212693

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: ATM — E2F1 (direct interaction, enzymatic study) Lin et al., Genes Dev 2001*
• IRef Hprd Interaction: E2F1 — ATM (in vitro) Lin et al., Genes Dev 2001*