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IL10 — ITIH4
Text-mined interactions from Literome
Borghi et al., J Virol 1995
:
Monoclonal antibodies to gp120 strongly inhibited recombinant
gp120 induced
IL-10 secretion by monocytes/macrophages
Shearer et al., Pediatr Res 1993
(HIV Infections) :
Recent data suggest that multiple and independent immunosuppressive factors, including
gp120 induced suppression and
IL-10 , are responsible for the loss of TH function seen in HIV infected individuals before development of symptoms
Taoufik et al., Blood 1997
:
Human immunodeficiency virus
gp120 inhibits
interleukin-12 secretion by human monocytes : an indirect interleukin-10 mediated effect ... We showed that in human monocyte cultures,
HIV-gp120 induces a significant
IL-10 synthesis, which in turn inhibits IL-12 subunits mRNA accumulation and protein secretion after SAC-activation