Gene interactions and pathways from curated databases and text-mining

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BCL2 — IL10

Text-mined interactions from Literome

Alas et al., Cancer Res 2001 (Burkitt Lymphoma) : The objective of this study was to delineate the signaling pathway by which Bcl-2 is controlled by Rituximab and IL-10 ... Hence, Rituximab induced down-regulation of IL-10 expression is responsible for the down-regulation of Bcl-2 and sensitization of NHL cells by therapeutic drugs
Kalechman et al., J Biol Chem 2004 (Glomerulonephritis) : IL-10 increased MC expression of Bcl-2 and Bcl-X1 and simultaneously decreased the levels of p27kip1
Santner-Nanan et al., J Immunol 2013 : Indeed, in vitro data in both humans and mice demonstrate that IL-10 upregulates Bcl-2 specifically in Treg cells but not non-Treg cells
Weber-Nordt et al., Blood 1996 : Interleukin-10 increases Bcl-2 expression and survival in primary human CD34+ hematopoietic progenitor cells
Cohen et al., Immunology 1997 : We therefore investigated whether IL-10 might affect the Bcl-2 expression on cultured T cells