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IL6 — PDGFA
Text-mined interactions from Literome
Franchimont et al., Endocrinology 1995
:
Although
PDGF AA increased
IL-6 mRNA levels, its effect was less pronounced than that of PDGF BB
Zhang et al., J Dermatol 1995
(Carcinoma, Squamous Cell) :
Prostaglandin E1 slightly inhibited PDGF-AB production, transforming growth factor beta 1
promoted PDGF-AB production and interferon-gamma,
interleukin-1 alpha, and tumor necrosis factor-alpha failed to exert any influence at all
Roth et al., Proc Natl Acad Sci U S A 1995
:
The three isoforms of the PDGF -- namely,
PDGF-AA , -AB, and -BB --
induced the expression of the
IL-6 gene and proliferation of the nontransformed cells
Takemura et al., J Rheumatol 1998
(Scleroderma, Systemic) :
Platelet derived growth factor (PDGF)-AA and PDGF-BB, a major growth factor in serum,
induced significant
IL-6 production by SSc fibroblasts