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DISC1 — TNFRSF10B

Text-mined interactions from Literome

Earel et al., Cancer Res 2006 (Urinary Bladder Neoplasms) : The increased TRAIL-R2 levels also resulted in accelerated death inducing signaling complex ( DISC ) formation, caspase activation, and loss of mitochondrial membrane potential, which all contributed to the increase in tumor cell death
Koschny et al., Hepatology 2007 : RNA interference and TRAIL receptor blockage experiments revealed that in bortezomib treated hepatoma cells TRAIL-R1/TRAIL-R2 up-regulation, enhanced TRAIL DISC formation and cFLIPL down-regulation in addition to accumulation of Bak cooperatively sensitized for TRAIL