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CCND1 — HGF

Text-mined interactions from Literome

Osada et al., Cancer 2001 (Stomach Neoplasms) : Epidermal growth factor (EGF) or hepatocyte growth factor (HGF) stimulated increase of cyclin D1 protein after 12 hours and increased DNA content after 3 days in culture
Ajioka et al., J Cell Biochem 2002 : Etn and HGF synergistically induced cyclin D(1) , A and B expression, however, only cyclin B but not cyclin A formed a complex with Cdc2
Takami et al., Am J Respir Cell Mol Biol 2002 : IFN-gamma does not interfere with the effects of HGF on either ERK activation or cyclin D1 induction ; however, it prevents the downregulation of p27 ( kip1 ) CDK inhibitor that takes place in response to a combination of HGF and serum
Recio et al., Oncogene 2002 (Melanoma) : We here report that HGF/SF can induce cyclin D1 expression in mouse melanoma cells, and that this up-regulation is mediated in part by the activating transcription factor-2 ( ATF-2 ) ... However, transcriptional up-regulation of cyclin D1 by HGF/SF was partially inhibited by the p38 kinase-specific inhibitor, and cyclin D1 protein induction was partially blocked by a dominant negative ATF-2 mutant
García-Trevijano et al., Gastroenterology 2002 : Accordingly, we found that S-adenosylmethionine inhibits hepatocyte growth factor induced cyclin D1 and D2 expression, activator protein 1 induction, and hepatocyte proliferation
Martínez-Chantar et al., Gastroenterology 2006 : How SAM regulates hepatocyte growth is unclear, but because SAM blocks hepatocyte growth factor (HGF) induced cyclin D1 expression and DNA synthesis without affecting HGF induced extracellular signal regulated kinase phosphorylation, the mitogen activated protein kinase ( MAPK ) pathway is probably not the target
Oka et al., Biochem Biophys Res Commun 2013 : Using this in vitro model, we provide evidence that not only induction of cyclin-D1 by HGF but also up-regulation of cyclin-E1 by proline is required for hepatocytes to enter the S-phase