Durmowicz et al., Gene 2002
:
Over-expression of both Lef-1 and beta-catenin significantly increased EDA transcription in co-transfection studies ... In addition, indirect stabilization of endogenous beta-catenin stimulated EDA transcription 4- to 13-fold
Närhi et al., Development 2008
:
Forced epithelial stabilization of beta-catenin resulted in precocious and excessive induction of hair follicles even in the absence of Eda/Edar signaling, a pathway essential for primary hair placode formation