Siegel et al., Proc Natl Acad Sci U S A 2011
(Brain Ischemia) :
miR-23a directly bound the 3 ' UTR of XIAP, and miR-23a inhibition led to an increase in XIAP mRNA in vitro, demonstrating that XIAP is a previously uncharacterized target for miR-23a Xie et al., Oncogene 2013
(Neoplasms) :
Interference with miR-24 's binding of the critical seed region, resulting from site directed mutagenesis of the 3'UTR, significantly abrogated miR-24 's effects on XIAP expression