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NFKB1 — TNFRSF17
Text-mined interactions from Literome
Hatzoglou et al., J Immunol 2000
(MAP Kinase Signaling System) :
We also show that overexpression of
BCMA in 293 cells
activates NF-kappa B , Elk-1, the c-Jun N-terminal kinase, and the p38 mitogen activated protein kinase ... Furthermore, as
BCMA is lacking a `` death domain '' and its overexpression
activates NF-kappa B and c-Jun N-terminal kinase, we can reasonably hypothesize that upon binding of its corresponding ligand BCMA transduces signals for cell survival and proliferation
Shu et al., Proc Natl Acad Sci U S A 2000
:
Overexpression of
BCMA activates
NF-kappaB , and this activation is potentiated by TALL-1 ... Moreover,
BCMA mediated
NF-kappaB activation is inhibited by dominant negative mutants of TNF receptor associated factor 5 (TRAF5), TRAF6, NF-kappaB inducing kinase (NIK), and IkappaB kinase (IKK)