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ALK — PI3
Text-mined interactions from Literome
Slupianek et al., Cancer Res 2001
(Cell Transformation, Neoplastic...) :
Our studies showed that
NPM/ALK , similar to other members of this family,
activates phosphatidylinositol 3-kinase (PI3K) and its downstream effector, serine/threonine kinase ( Akt )
Vega et al., Cancer Res 2006
(Lymphoma, Large B-Cell, Diffuse) :
Previously,
nucleophosmin-ALK has been shown to
activate phosphatidylinositol 3-kinase (PI3K) and its downstream effector, the serine/threonine kinase AKT