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CCDC88A — EPHB2
Text-mined interactions from Literome
Lee et al., J Immunol 2009
(Inflammation...) :
Silencing of
APE1 attenuated cyclin D1/cyclin dependent kinase 4 expression and phosphorylation of
ERK1/2 and Akt, thereby affecting keratinocyte proliferation
Wang et al., Toxicology 2013
:
Here, we explore whether
APE1 and reactive oxygen species ( ROS )
affect ERK signaling and cell cycle progression following Pb exposure ... Intriguingly, the capability of Pb to activate ERK was abolished under siAPE1 or E3330 co-treatments ; conversely, forced expression of
APE1 up-regulated the
ERK activation by Pb or serum in both Cys65-redox activity dependent and independent manners