UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2: VEGFR2 (dimer)/VEGFA (dimer)/TSAd complex (KDR-VEGFA-SH2D2A) → TsAd (SH2D2A) (modification, collaborate) Wu et al., J Biol Chem 2000 *, Matsumoto et al., EMBO J 2005 *
Evidence: physical interaction
NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2: VEGFR2 (dimer)/VEGFA (dimer)/TSAd complex (KDR-VEGFA-SH2D2A) → VEGFR2 (dimer)/VEGFA (dimer) complex (KDR-VEGFA) (modification, collaborate)
Wu et al., J Biol Chem 2000 *, Matsumoto et al., EMBO J 2005 *
Evidence: physical interaction
NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2: TsAd (SH2D2A) → VEGFR2 (dimer)/VEGFA (dimer) complex (KDR-VEGFA) (modification, collaborate)
Wu et al., J Biol Chem 2000 *, Matsumoto et al., EMBO J 2005 *
Evidence: physical interaction
Reactome Reaction: SH2D2A → VEGFA (reaction) Wu et al., J Biol Chem 2000 *, Matsumoto et al., EMBO J 2005 *, Ruan et al., EMBO J 2012, Sun et al., J Exp Med 2012 *
Reactome Reaction: SH2D2A → VEGFA (indirect_complex) Wu et al., J Biol Chem 2000 *, Matsumoto et al., EMBO J 2005 *