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TIMP3 — VEGFA

Text-mined interactions from Literome

Qi et al., Nat Med 2003 (Neovascularization, Pathologic) : In this study we demonstrate the ability of TIMP3 to inhibit vascular endothelial factor ( VEGF ) -mediated angiogenesis and identify the potential mechanism by which this occurs : TIMP3 blocks the binding of VEGF to VEGF receptor-2 and inhibits downstream signaling and angiogenesis
Neill et al., J Biol Chem 2012 (Neovascularization, Pathologic) : Decorin antagonizes the angiogenic network : concurrent inhibition of Met, hypoxia inducible factor 1a, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3