Gene interactions and pathways from curated databases and text-mining

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IL10 — MMP1

Text-mined interactions from Literome

Meisser et al., Mol Hum Reprod 1999 : The aim of this study was to determine the effects of tumour necrosis factor alpha (TNF), interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
John et al., Exp Lung Res 2002 (Pneumonia, Bacterial...) : The endogenous production of IL-10 in AM of patients with sarcoidosis and the MMP downregulation by exogenous IL-10 suggest an involvement of IL-10 in MMP regulation
Ray et al., Arthritis Rheum 2003 (Osteoarthritis) : Overexpression of SAF-1 in OA chondrocytes increased the expression of the MMP1 promoter, and interference of endogenous SAF-1 activity by antisense SAF-1 messenger RNA inhibited interleukin-1 mediated MMP1 promoter activity
Sun et al., Connect Tissue Res 2003 (Arthritis, Rheumatoid) : Furthermore, the induction of the MMP expression and activities by interleukin-1 was suppressed by the oscillatory shear
Perianayagam et al., Eur J Clin Invest 2005 (Uremia) : We hypothesized that previously reported defective synthesis of IL-10 by immunocompetent cells exposed to a uraemic milieu may be due to impaired mitochondrial membrane potential ( MMP )
Radons et al., Int J Mol Med 2006 (Chondrosarcoma) : Surprisingly, IL-10 had no effect on IL-1 induced IL-6, pro-MMP1 , and pro-MMP13 secretion
Hu et al., Zhonghua Xin Xue Guan Bing Za Zhi 2008 (Myocardial Infarction...) : In vivo myocardial IL-10 transfer reduced myocardial MMP and collagen expression and increasing the TIMP expression
Coussens et al., Immunology 2009 (Tuberculosis) : We therefore determined the effects of 1alpha,25 ( OH ) ( 2 ) D ( 3 ) on expression, secretion and activity of a number of MMP and TIMP in M. tuberculosis infected human leucocytes ; we also investigated the effect of 1alpha,25 ( OH ) ( 2 ) D ( 3 ) on the secretion of interleukin-10 (IL-10) and prostaglandin E ( 2 ) ( PGE ( 2 ) ), both transcriptional regulators of MMP expression
Abe et al., J Nat Prod 2010 : The effects of these new compounds on interleukin-1ß induced production of matrix metalloproteinase-1 (MMP-1) in human dermal fibroblasts were examined
Gotoh et al., Connect Tissue Res 2013 : Extracellular ß-NAD ( + ) inhibits interleukin-1 induced matrix metalloproteinase-1 and -3 expression on human gingival fibroblasts
Langdon et al., Arthritis Rheum 1997 (Arthritis, Rheumatoid) : Oncostatin M stimulates monocyte chemoattractant protein-1- and interleukin-1 induced matrix metalloproteinase-1 production by human synovial fibroblasts in vitro
Stearns et al., Invasion Metastasis 1997 (Bone Neoplasms...) : However IL-10 may inhibit the production of matrix metalloproteases ( MMP ) and prevent the establishment of metastasis
Dean et al., J Biol Chem 1999 : We have previously shown that the pyridinyl imidazole SB 203580, which inhibits it, blocks the interleukin-1 induction of cyclooxygenase-2 (COX-2) and matrix metalloproteinase 1 and 3 mRNAs in fibroblasts
Wagner et al., J Neurooncol 1998 (Brain Neoplasms...) : In all but one cell line no enhancement of MMP expression by IL-10 was detected