Gene interactions and pathways from curated databases and text-mining

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IL10 — NOX1

Text-mined interactions from Literome

Tojo et al., J Hypertens 2005 (Hypertension, Renal) : Nicotinamide adenine dinucleotide phosphate ( NAD ( P ) H ) oxidase is regulated by angiotensin II, interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha via p38 mitogen activated protein kinase ( MAPK )
Perianayagam et al., Eur J Clin Invest 2005 (Uremia) : In contrast, apocynin, a selective NADPH oxidase inhibitor, did not inhibit ET-stimulated IL-10 production
Dang et al., FASEB J 2006 : This IL-10 effect could contribute to the tight regulation of NADPH oxidase activity at the inflammatory site
Kassan et al., Arterioscler Thromb Vasc Biol 2011 (Disease Models, Animal...) : These data demonstrate that IL-10 released from Tregs attenuates NADPH oxidase activity, which is a critical process in the improvement of microvascular endothelial function in hypertension, suggesting that Tregs/IL-10 could be a therapeutic target for treatment of vasculopathy in hypertension
Dammanahalli et al., J Hypertens 2011 : IL-10KO increased Nox1 protein expression, NADPH oxidase activity, and superoxide production in aortas