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PTK2 — TGFB1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: PTK2 → TGFB1 (decreases) Pechkovsky et al., J Biol Chem 2008*
  Evidence: we determined levels of Tyr397-FAK and Tyr416-Src phosphorylation following exposure to the disintegrin. Echistatin dramatically inhibited TGF1-induced c-Src kinase (Fig. 4B) and FAK phosphorylation (data not shown) in a concentration-dependent manner.....Fig. 5A demonstrates that TGF1 induced time-dependent phosphorylation of FAK on Tyr397

Text-mined interactions from Literome

Liu et al., Int J Hematol 2002 (Calcium Signaling...) : In contrast, TGF-beta1 induced an increase in intracellular free calcium concentration and PKC and PTK activity in HEL cells
Zhang et al., Zhonghua Zheng Xing Wai Ke Za Zhi 2005 (Cicatrix, Hypertrophic) : [ Signal roles of protein tyrosine kinase in transforming growth factor-beta1 , or interferon-gamma regulated proliferation and collagen synthesis by fibroblasts from hypertrophic scar and normal dermis ]
Sayers et al., Arterioscler Thromb Vasc Biol 2008 : We also show that FRNK expression is regulated by transforming growth factor ( TGF ) -beta and that forced expression of FRNK in cultured cells induces serum- and TGF-beta stimulated SM marker gene expression, whereas FRNK deletion or expression of a constitutively activated FAK variant attenuated SM gene transcription
Liu et al., Lab Invest 2009 (Liver Cirrhosis) : Furthermore, PDGF induced TGF-beta1 expression is inhibited by PTK/ZK
Mohamed et al., Am J Physiol Lung Cell Mol Physiol 2010 : Interestingly, selective inhibitors of PTK , PI3K, or MEK1/2 attenuated TGF-beta1 expression through blocking ERK1/2 phosphorylation and TGF-beta1 promoter activity in response to stretch