Gene interactions and pathways from curated databases and text-mining

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SLC22A3 — ZEB2

Text-mined interactions from Literome

Vandewalle et al., Nucleic Acids Res 2005 : SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions
Chua et al., Oncogene 2007 (Cell Transformation, Neoplastic...) : MCF10A cells chronically exposed to tumor necrosis factor alpha (TNFalpha), a potent NF-kappaB inducer, also exhibited the EMT-like phenotype and ZEB-1/ZEB-2 induction , both of which were reversed following TNFalpha withdrawal
Kong et al., Stem Cells 2009 (Neoplasm Invasiveness...) : Recent studies have shown that the miR-200 family regulates epithelial-mesenchymal transition (EMT) by targeting zinc-finger E-box binding homeobox 1 ( ZEB1 ) and ZEB2
Peña et al., Oncogene 2009 (Carcinoma...) : SNAI1, ZEB1 , E-cadherin ( CDH1 ), and vitamin D receptor (VDR) genes regulate the epithelial-mesenchymal transition (EMT) that initiates the invasion process of many tumor cells
Namba et al., Cell Death Differ 2010 (Pulmonary Fibrosis) : Smad interacting protein 1 ( a transcription factor regulating EMT ) and the Notch signaling pathway but not transforming growth factor-ß was shown to be involved in A771726 induced EMT-like phenotypes
Brabletz et al., EMBO Rep 2010 (Neoplasms) : Zinc-finger enhancer binding ( ZEB ) transcription factors ( ZEB1 and ZEB2 ) are crucial EMT activators , whereas members of the miR-200 family induce epithelial differentiation
Oba et al., PloS one 2010 (Fibrosis...) : miR-200 family members have been previously shown to inhibit EMT by reducing the expression of ZEB-1 and ZEB-2 which are known repressors of E-cadherin
Stinson et al., Science signaling 2011 (Breast Neoplasms...) : TRPS1 inhibited EMT by directly repressing expression of ZEB2 ( Zinc finger E-box binding homeobox 2 )