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PDC — TLR4

Text-mined interactions from Literome

Boor et al., Am J Transplant 2006 (Postoperative Complications...) : However, non-apoptosis inducing concentrations of prednisolone suppressed interferon-alpha production, upregulation of co-stimulatory molecules and allo-stimulatory capacity of TLR stimulated PDC ... Moreover, prednisolone suppresses the functions of TLR stimulated PDC
Watarai et al., Proc Natl Acad Sci U S A 2008 : Thus, PDC-TREM is responsible for IFN-alpha production, whereas TLR signals are essential for PDC-TREM expression
Bekeredjian-Ding et al., Immunology 2009 (Head and Neck Neoplasms) : Finally, in TLR stimulated PDC , PGE ( 2 ) and TGF-beta reduce the CCR7 : CXCR4 ratio, suggesting that PDC are impaired in their ability to migrate to tumour draining lymph nodes but are retained in stromal cell derived factor 1 (SDF-1) expressing tissues