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BCL2 — WT1

Text-mined interactions from Literome

Fukuzawa et al., Pediatr Dev Pathol 2004 (Kidney Neoplasms...) : Myogenesis in Wilms ' tumors is associated with mutations of the WT1 gene and activation of Bcl-2 and the Wnt signaling pathway ... Bcl-2 was expressed in rhabdomyoblasts, but not in blastemal cells undergoing apoptosis, suggesting that WT1 regulates Bcl-2 positively in the epithelial pathway, but negatively in the myogenic pathway
Bansal et al., J Biol Chem 2012 (Leukemia, Myeloid, Acute) : Collectively, our results suggest that WT1 dependent Bcl-xL overexpression contributes to TRAIL resistance in myeloid leukemias