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APC — IL6
Text-mined interactions from Literome
Zhong et al., Anesthesiology 2004
(Myocardial Infarction...) :
APC with sevoflurane attenuated NF-kappaB activation and
reduced the expression of tumor necrosis factor alpha,
interleukin 1, intercellular adhesion molecule 1, and inducible nitric oxide synthase
Xue et al., Exp Cell Res 2004
:
APC also significantly
increased the production of
IL-6 and IL-8 and suppressed calcium- and LPS stimulated NF-kappaB activity
Mehrotra et al., Immunology 2004
(Melanoma) :
Among the various microenvironmental factors,
interleukin-10 (IL-10) exhibits a potent immunosuppressive
effect on
antigen presenting cells (APC)
Li et al., J Zhejiang Univ Sci B 2006
:
APC can further
increase the level of
IL-6 and IL-8 induced by LPS
Wang et al., Journal of thrombosis and haemostasis : JTH 2011
(MAP Kinase Signaling System...) :
Moreover, both
APC and APC-2Cys
inhibited production of TNFa and
IL-6 in vivo by attenuating the ischemia/reperfusion induced JNK and NF-?B signaling pathways
Piuvezam et al., J Immunol 1993
:
T cell lines generated against Tct proliferated in response to parasite lysate only in the
presence of autologous
APC and produced IL-2,
IL-6 , and IFN-gamma but not IL-4 in response to PMA plus ionomycin
Gray et al., Haemostasis 1996
:
Activated protein C (APC) augmented LPS stimulation of HUVEC and further
increased the production of tissue factor and
IL-6
Behboudi et al., Cytokine 1997
:
Among the various combinations of QH-A and QH-C tested and also the original semipurified spikoside, the QH 7.0.3 matrix was the most efficient formulation for
activation of
IL-6 production by
APC
Morein et al., Dev Biol Stand 1998
:
Further, iscoms
induce APC to produce IL-1,
IL-6 and IL-12 and a TH1 type of response with enhanced IL-2 and IFN-gamma production