Gene interactions and pathways from curated databases and text-mining

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ARF6 — EPHB2

Text-mined interactions from Literome

Lachat et al., Oncogene 2004 (Glioma) : INK4a/Arf is required for suppression of EGFR/DeltaEGFR ( 2-7 ) -dependent ERK activation in mouse astrocytes and glioma
Hoover et al., Methods Enzymol 2005 (Neoplasm Invasiveness) : These findings demonstrate a critical role for ARF6 in ERK activation and tumor cell invasion ... To investigate the role of ARF6 in tumor cell invasion and ERK activation, a number of methods were employed
Tushir et al., EMBO J 2007 : ARF6 dependent activation of ERK and Rac1 modulates epithelial tubule development ... Second, ARF6 induced ERK activation regulates Rac1 activation during tubule initiation through the expression of the receptor for urokinase type plasminogen activator
Parachoniak et al., Dev Cell 2011 : Met recycling, sustained ERK activation, and migration require interaction of GGA3 with Arf6 and an unexpected association with the Crk adaptor