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CXCL12 — FUT1
Text-mined interactions from Literome
Hong et al., Hepatology 2009
(Liver Cirrhosis) :
We therefore examined whether HSCs express CXCR4 in vivo and in vitro and explored whether
SDF-1alpha/CXCR4 receptor engagement
promotes HSC activation, fibrogenesis, and proliferation ... Extracellular signal regulated kinase 1/2 and phosphoinositide 3-kinase pathways mediate
SDF-1alpha induced effects on
HSC expression of collagen I and proliferation
Kidd et al., Exp Hematol 2011
:
We recently reported the importance of the extracellular protease CD26 ( dipeptidylpeptidase IV ) in regulating
HSC responses to
CXCL12 , as well as modulating HSC trafficking into and out of the bone marrow
Nischalke et al., J Hepatol 2012
(Disease Progression...) :
Thus,
CXCL1 might
contribute to
HSC activation and fibrogenesis