Gene interactions and pathways from curated databases and text-mining

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CXCL8 — KSR2

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: CXCL8 → KSR2 (decreases) Channavajhala et al., J Biol Chem 2003*
    Evidence: Cot-induced interleukin-8 production in HeLa cells is almost completely inhibited by the concurrent expression of hKSR-2, whereas transforming growth factor beta-activated kinase 1 (TAK1)/TAK1-binding protein 1 (TAB1)-induced interleukin-8 production is not affected by hKSR-2 co-expression.