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TLR5 — TLR9
Text-mined interactions from Literome
An et al., Immunology 2002
:
While inhibition of extracellular signal related kinase and NF-kappaB activation suppressed the up-regulation of the expression of TLR2,
TLR4 and TLR9 mRNA, inhibition of p38 kinase prevented the up-regulation of TLR2 and TLR4 mRNA expression but
enhanced the up-regulation of
TLR9 expression
Duez et al., Eur J Dermatol 2006
(Asthma...) :
During the allergic reaction,
TLR engagement on DC directs the polarization of the T cell response and, while TLR2 and TLR4 may favour both Th1 and Th2 responses,
TLR9 induces the development of regulatory T cells
van de Veerdonk et al., Immunobiology 2008
(Candidiasis) :
In conclusion,
TLR9 is a pathogen-recognition receptor for C. albicans, and
TLR9 is
involved in the induction of cytokines in response to C. albicans
Deng et al., Circ Res 2009
(Disease Models, Animal...) :
However, the architecture of the evolving inflammation is ligand-specific
; TLR4 ligands
cause transmural panarteritis and
TLR5 ligands promote adventitial perivasculitis
Charavaryamath et al., Gut microbes 2011
:
Finally,
Toll-like receptor (TLR)-4 expression was decreased but
TLR-5 and -6 expression
increased in ileal segments
Kim et al., FEMS Microbiol Lett 2012
(Inflammation) :
L. plantarum genomic DNA mediated inhibition of signaling pathway and tumor necrosis factor-alpha was accompanied by the suppression of toll-like receptor (TLR) 2, TLR4, and
TLR9 and the induction of interleukin-1 receptor associated kinase M, a negative
regulator of
TLR
Kwissa et al., Blood 2012
:
In the draining lymph nodes ( LNs ), consistent with the effects in blood, all
TLR-Ls induced expansion of CD14 ( + ) monocytes, but only TLR7/8-L and
TLR9-L expanded the activated CD14 ( + ) CD16 ( + ) cells
Deng et al., Immunol Cell Biol 2013
:
The
TLR signals that regulate the phagocytic ability of macrophages were also
induced by TLR4 and
TLR5 activation
Zhao et al., Fish Shellfish Immunol 2013
(Ciliophora Infections...) :
TLR9 was
induced in the skin and gill, whereas
TLR21 was induced in the head kidney and spleen after infection