◀ Back to LEP

IL1A — LEP

Text-mined interactions from Literome

Gabay et al., J Clin Endocrinol Metab 2001 : However, leptin had no effect on the expression or secretion of IL-1 in THP-1 cells
Hosoi et al., Brain Res 2002 : We report here that peripherally applied leptin increased interleukin (IL)-1beta transcripts in many regions of the brain such as the hypothalamus, the hippocampus, the cortex, the cerebellum and the brainstem
Gonzalez et al., Mol Hum Reprod 2003 : Leptin stimulated IL-1 antagonist ( IL-1Ra ), IL-1beta secretion and expression of IL-1 receptor type I (IL-1R tI) in both cell types
Layé et al., J Soc Biol 2003 (Anorexia...) : Leptin is tightly regulated by IL-1 , suggesting the involvement of this hormone in the anorexia of infection
Sato et al., Adv Exp Med Biol 2003 (Anorexia...) : Tumor Necrosis Factor (TNF) and/or interleukin-1 (IL-1) stimulate leptin release, but not insulin
Sachot et al., J Physiol 2004 (Anorexia...) : Previous studies have demonstrated that LPS induces leptin synthesis and secretion in the periphery, and that the action of leptin on appetite suppression and fever are dependent on brain interleukin (IL)-1beta
Pinteaux et al., J Neurochem 2007 (Encephalitis) : Recently we demonstrated that the effects of leptin are, at least in part, mediated by the release of interleukin (IL)-1beta in the brain
Carino et al., Int J Cancer 2008 (Adenocarcinoma...) : However, IL-1beta was only increased by leptin in benign primary-EEC
Padidar et al., J Cell Physiol 2011 (Inflammation...) : IL6, IL1ß and CXCL1 were up-regulated by leptin and localised to discrete cells in gut epithelium, lamina propria, muscularis and at the peritoneal serosal surface
Guo et al., PloS one 2011 (Mammary Neoplasms, Animal) : To test this hypothesis, leptin 's effects on the expression and activation of Notch signaling pathway and VEGF/VEGFR-2/IL-1 were determined in mouse ( 4T1, EMT6 and MMT ) breast cancer cells
Ake et al., Kobe J Med Sci 1994 : The results suggest that OBs produce NO in response to IL-1 alpha and OB-induced NO may play a role in OB-OC interaction in the inflammatory process