Gene interactions and pathways from curated databases and text-mining

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IL6 — TFPI

Text-mined interactions from Literome

Kereveur et al., Thromb Haemost 2001 : Production of tissue factor pathway inhibitor in cardiomyocytes and its upregulation by interleukin-1
Mirshahi et al., Blood Coagul Fibrinolysis 2002 (Arteriosclerosis...) : IL-6 and LIF reduced also TFPI secretion, which could explain why the PCA of SMC lysates treated by IL-6 or LIF was increased, despite an absence of effect on TF expression
Fonseca et al., J Trauma 2005 : The presence of NE and EPI increased IL-6 levels in a dose dependent fashion
Lang et al., J Trauma 2008 (Sepsis) : Epi acutely increased TNF-alpha IL-6 and IL-1beta mRNA content in muscle ( 3- to 40-fold )
Tokuda et al., Horm Metab Res 2008 : In the present study, we investigated the exact mechanism of IL-6 and the effects of ( - ) -epi-gallocatechin gallate (EGCG), one of the major green tea flavonoids, on the synthesis of IL-6
Gray et al., Haemostasis 1996 : Truncated tissue factor pathway inhibitor ( TFPI1-161 ) inhibited LPS induced MNC tissue factor and IL-6 production, but was unable to prevent LPS stimulatory activity on HUVEC