Gene interactions and pathways from curated databases and text-mining

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CTNNB1 — SRP54

Text-mined interactions from Literome

Gonçalves et al., RNA 2008 (Colorectal Neoplasms) : In contrast, inhibition of endogenous beta-catenin signaling by a dominant negative TCF4 construct down-regulated both luciferase reporter and SRp20 expression ... We further demonstrate that the beta-catenin/TCF4 mediated increase in SRp20 protein levels is sufficient to modulate alternative splicing decisions in the cells
Gonçalves et al., Hum Mol Genet 2009 (Colorectal Neoplasms) : Both splicing factors were found to be regulated by upstream signaling pathways : the inhibition of the phosphatidylinositol 3-kinase pathway increased protein levels of ASF/SF2 and promoted Rac1b, whereas activation of beta-catenin/TCF4 increased expression of SRp20 and inhibited that of Rac1b